13 March, 2008
IHPBA 2008
The 8th World Congress of IHPBA will be held from February 27th to March 2nd, 2008, in Mumbai, India. The four-day conference will be the largest international, interdisciplinary forum.
MTA Related presentations and posters include:
A Comparison of Lesions Produced by Radiofrequency, Cryotherapy and Microwave Ablation in the Liver.
David Lloyd presents Andy Strickland's small animal model which compares the unablated/ablated boundary and the heat sink effect in ablations induced by three ablation modalities. The results showed histologically that RF and Cryotherapy demonstrated irregular boundaries, intra-lesional viable hepatocytes, particularly in cells in proximity to blood vessels and a large inflammatory response between the two zones. Microwave produced a histologically sharp demarcation between the two zones, no intra-lesional or perivascular survival and a completely uniform ablation area.
Microwave Ablation is an Effective Method of Treating Patients with Unresectable Colorectal Liver Metasteses.
This poster by Neil Bhardwaj presents survival data on a consecutive series of 25 patients surviving 1 year post microwave ablation. A total of 80 tumours (mean 21mm, range 8-62mm) were ablated with 150W microwave for 2-4 minutes single insertions. 14 patients are alive post ablation of which 7 are disease free (mean f/u 27 months, range 12-41). 7 are alive with distal intra-hepatic recurrence (mean f/up 35 months, range 18-48) of which 1 patient also has recurrance at the treated site. Overall recurrance rate at ablated site 1.25%. Of those with recurrance 86% are alive more than 2 years post ablation. Eleven patients died surviving an average of 25 months range 12-41.
Large Unresectable Liver Tumours Treated Successfully with Microwave Ablation.
This poster by Neil Bhardwaj tracks 17 consecutive patients with single or multiple unresectable tumours measuring at least 3cm. A total of 48 lesions were treated, 26 of which were greater than 3cm (mean 3.9cm, range 3-7cm). Most were treated with a single insertion of the applicator at 150W for 2-3 minutes. Nine patients underwent concommitant liver resection. No ablation related complications were noted. Eight patients are alive of whom 4 are disease free (mean 34 months, range 18-41). Four have distal intra-hepatic recurrance (mean 40 months, range 32-48) of which one also has local recurrance at the ablative site. Nine patients died (mean 19 months, range 12-42) of either hepatic or extra-hepatic disease progression. None had evidence of local recurrance on their last scan. All patients were declared inoperable prior to coming to Leicester Royal Infirmary and 60% were alive 2 years post ablation. The local recurrance rate of 2% compares favourably to RF and cryoablation.
